Epigallocatechin-3-Gallate Helps Mice Swim Longer

Experts from Liaoning Normal University (Dalian, China) have conducted a study on the anti-fatigue effect of green tea polyphenols. To this end, four groups of mice (12 mice each) received four types of diet for 28 days and then were tested for fatigue by forced swimming. The first group of mice received no catechins, the second group received 50 milligrams of Epigallocatechin-3-Gallate (EGCG) per kilogram of weight per day, the third group — 100 mg, the fourth — 200 mg. The forced swimming test demonstrated that the mice, that received no catechins, could swim for 15 minutes before they were exhausted, the second group (that received 50 mg of EGCG) — about 20 minutes, the third group (100 mg of EGCG) — about 22 minutes and, finally, the fourth group (200 mg of EGCG) — about 28 minutes.

Photo credit: Olga Nikandrova

The monument to the laboratory mouse, by the way, is located not that far from Dalian. In Novosibirsk, Russia.